Learning objectives

Name aliphatic compounds including single-ring cyclic compounds, amides and esters, and aromatic compounds with one benzene ring such as 3-nitrobenzoic acid and 2,4,6-tribromophenol

Use the terms electrophilic substitution and addition–elimination to classify reaction mechanisms met at A Level

Explain how a pair of enantiomers can be told apart only by the direction in which they rotate plane-polarised light and, sometimes, by their effect in the body, and use the terms optically active and racemic mixture

Explain why drug manufacturers aim for a single enantiomer, including separating racemic mixtures and using chiral catalysts

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